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Dr. Melman and Dr. Christ have authored hundreds of scientific papers and only a small sample is shown here. |
Publications
Gene Therapy in the Management of Erectile Dysfunction (ED): Past, Present, and Future The mechanism of opiorphin-induced experimental priapism in rats involves activation of the polyamine synthetic pathway Metrics for evaluation of age-related changes in erectile capacity in a rodent model. Effects of ageing and streptozotocin-induced diabetes on connexin43 and P2 purinoceptor expression in the rat corpora cavernosa and urinary bladder. Alterations in bladder function associated with urothelial defects in uroplakin II and IIIa knockout mice. Smooth-Muscle-Specific Gene Transfer with the Human Maxi-K Channel Improves Erectile Function and Enhances sexual Behavior in Atherosclerotic Cynomolgus Monkeys. Markers of erectile dysfunction. Effects of hyperglycemia on rat cavernous nerve axons: a functional and ultrastructural study. The opiorphin gene (ProL1) and its homologues in erectile physiology Gene Therapy for male erectile dysfunction Gene transfer with a vector expressing Maxi-K from a smooth muscle-specific promoter restores erectile function in the aging rat. Ageing causes cytoplasmic retention of Maxi-K channels in rat corporal smooth muscle cells hSMR3A as a Marker for Patients With Erectile Dysfunction Gene Therapy for Male Erectile Dysfunction hMaxi-K Gene Transfer in Males with Erectile Dysfunction: Gene transfer for the therapy of erectile dysfunction: progress in the 21st century Evaluation Of Two Techniques Of Partial Urethral Obstruction In The Male Rat Model Of Bladder Outlet Obstruction The First Human Trial for Gene Transfer Therapy for the Treatment of Erectile Dysfunction: Preliminary Results. Intracorporal injection of hSlo cDNA restores erectile capacity in STZ-diabetic F-344 rats in vivo. The successful long-term treatment of age related erectile dysfunction with hSlo pcDNA in rats in vivo. Potassium Channels And Human Corporeal Smooth Muscle Cell Tone: Diabetes and relaxation of human corpus cavernosum smooth muscle by adenosine triphosphate sensitive potassium channel openers. Potassium channels and human corporeal smooth muscle cell tone: further evidence of the physiological relevance of the maxi-k channel subtype to the regulation of human corporeal smooth muscle tone in vitro. Bladder injection of 'naked' hSlo/pcDNA3 ameliorates detrusor hyperactivity in obstructed rats in vivo Significant physiological roles of ancillary penile nerves on increase in intracavernous pressure in rats: experiments using electrical stimulation of the medial preoptic area. Comparative studies of the maxi-K(KCa) channel in freshly isolated myocytes of human and rat corpora Characterization of ATP-sensitive potassium channels in human corporal smooth muscle cells. A stretch-sensitive Cl channel in human corpus cavernosal myocytes. Intracorporal injection of hSlo cDNA in rats produces physiologically relevant alterations in penile function The application of gene therapy to the treatment of erectile dysfunction Molecular studies of human connexin 43 (Cx43) expression in isolated corporal tissue strips and cultured corporal smooth muscle cells. |